AC-43492 - n-acetyl-d-galactosamine-98 | 1811-31-0

Uridine-5'-diphospho-a-D-galactose disodium salt

UDP-a-D-Galactose disodium salt is a donor substrate for galactosyltransferases employed in the biosynthesis of galactose-containing oligosaccharides[1].

<p>Applications Uridine Diphosphate-α-D-[UL-13C6]galactose Disodium Salt is a labelled synthetic glycan that is used in drug innovation and discovery.<br>References Matsushita, T. et al.: J. Am. Chem. Soc., 132, 16651 (2010);<br></p>

<p>UDP-a-D-galactose disodium salt (UDP-Gal) is a sugar-nucleotide substrate of galactosyltransferases. It’s used as the donor of galactose in the biosyntheses of glycoproteins and glycolipids. Its low cellular content is also hypothetically linked to the defective galactosylation in galactosemia.</p>

<p>UDP-a-D-galactose disodium salt is a nucleotide sugar that is used in the synthesis of oligosaccharides. It is also used to identify mammalian cells that express UDP-galactose:quinone oxidoreductase, which are responsible for synthesizing the sugar. It is a building block of the influenza virus and has been shown to inhibit viral growth by interfering with RNA synthesis. This compound can be synthesized using solid-phase synthesis or multienzyme strategy.</p>