AC-46218 - saxagliptin | 361442-04-8
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Saxagliptin
CAS:Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.Formula:C18H25N3O2Purity:99.17% - 99.95%Color and Shape:SolidMolecular weight:315.41Saxagliptin
CAS:Controlled ProductStability Temperature Sensitive
Applications Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.
References Feng, J., et al.: J. Med. Chem., 50, 2297 (2007), Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008), Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008),Formula:C18H25N3O2Color and Shape:White SolidMolecular weight:315.41Saxagliptin
CAS:DPP-4 enzyme inhibitor; anti-diabetic
Formula:C18H25N3O2Color and Shape:White PowderMolecular weight:315.41 g/mol
