Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3→5)-disulfide

CAS: 128517-07-7

Ref. AN-AG000Y5C

Product Information

• Name: Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3→5)-disulfide
• Synonyms: [u'FK228', u'FR 901228', u'FR-901228', u'FR901228', u'istodax', u'romidepsin', u'Romidepsin', u'Istodax', u'FK228', u'Chromadax', u'Antibiotic FR 901228', u'Depsipeptide', u'FR901228', u'128517-07-7', u'FR-901228', u'NSC-630176', u'FK-228', u'C24H36N4O6S2', u'FR 901228', u'FK 228', u'CHEMBL343448', u'CHEBI:61080', u'NSC630176', u'NSC754143', u'UNII-CX3T89XQBK', u'NSC 630176', u'(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone', u'(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone', u'(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone', u'Istodax (TN)', u'CX3T89XQBK', u'HDInhib_000006', u'romidepsina', u'romidepsine', u'romidepsinum', u'OXA-12,8,20,23-TETRAZABICYCLO[8.7.6]TRICOSANE, CYCLIC PEPTIDE DERIV.', u'(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo(8.7.6)tricos-16-ene-3,6,9,19,22-pentone', u'L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide', u'L-Valine, N-(3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-, xi-lactone, cyclic (1-2)-disulfide, (S-(E))-', u'FK-901228', u'Probes1_000153', u'Probes2_000337', u'AC1NS1N3', u'Romidepsin (JAN/USAN/INN)', u'SCHEMBL677497', u'GTPL7006', u'Romidepsin, >=98% (HPLC)', u'BDBM19151', u'AOB1853', u'Romidepsin (FK228 ,depsipeptide)', u'Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl] Cyclic (35)-Disulfide', u'ZINC3935130', u'2692AH', u'MFCD18433404', u's3020', u'API0005301', u'CS-0985', u'NSC-754143', u'HY-15149', u'LS-161318', u'D06637', u'W-5757', u'49300-EP2298768A1', u'49300-EP2311840A1', u'AB01273968-01', u'SR-01000941579', u'SR-01000941579-1', u'L-Valine,3-didehydro-2- aminobutanoyl-,.xi.-lactone, cyclic (1.fwdarw.2)-disulfide', u'L-Valine,3-didehydro-2-aminobutanoyl-,.xi.-lactone, cyclic (1.fwdarw.2)-disulfide', u'(E)-(1S,10S,21R)-7-[(Z)-Ethylidene]-4,21-diisopropyl-2- oxa-12,13-dithia-5,8,20,23- tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone', u'(E)-(1S,10S,21R)-7-[(Z)-Ethylidene]-4,21-diisopropyl-2- oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone', u'[S-(E)]-N-(3-Hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-L-valine (4-1)-Lactone Cyclic (12)-Disulfide', u'Chromadax (TN)', u'Romidepsin (USAN)', u'Romidepsin [USAN]', u'Romidepsin [USAN:INN]', u'D0L7LC', u'C24-H36-N4-O6-S2', u'CID5352062', u'CS-T-61146', u'C087123', u'Romidepsin, 98%, a potent HDAC1 and HDAC2 inhibitor - 1MG 1mg', u'Cyclo((2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl), cyclic (35)-disulfide'], Fr 901228, Romidepsin, (1R,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
• CAS: 128517-07-7
• Brand: Indagoo

Chemical properties

• Molecular weight: 540.6958
• Formula: C₂₄H₃₆N₄O₆S₂
• Purity: 98%
• Color/Form: Solid
• InChI: InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1
• InChI key: OHRURASPPZQGQM-GCCNXGTGSA-N