5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine

CAS: 1032900-25-6

Ref. AN-AG003ABY

Product Information

• Name: 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine
• Synonyms: [u'5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine', u'ceritinib', u'LDK378', u'Zykadia', u'ceritinib', u'LDK378', u'1032900-25-6', u'ZYKADIA', u'NVP-LDK378-NX', u'LDK 378', u'LDK-378', u'UNII-K418KG2GET', u'5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine', u'Eritinib (LDK378)', u'Ceritinib (LDK378)', u'K418KG2GET', u'CHEMBL2403108', u'CHEBI:78432', u'AK174337', u'C28H36ClN5O3S', u'5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine', u'5-Chloro-N~2~-[5-Methyl-4-(Piperidin-4-Yl)-2-(Propan-2-Yloxy)phenyl]-N~4~-[2-(Propan-2-Ylsulfonyl)phenyl]pyrimidine-2,4-Diamine', u'5-Chloro-N2-(5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl)-N4-(2-(propane-2-sulfonyl)phenyl)pyrimidine-2,4-diamine', u'5-Chloro-N2-[2-isopropoxy-5-Methyl-4-(4-piperidyl)phenyl]-N4-(2-isopropylsulfonylphenyl)pyriMidine-2,4-diaMine', u'5-Chloro-N4-[2-[(1methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine;5-Chloro-N4-[2-[(1methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine', u'Ceritinib [USAN:INN]', u'ceritinibum', u'5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine', u'Zykadia (TN)', u'LDK378 Certinib', u'Ceritinib(LDK378)', u'LDK378(Ceritinib)', u'LDK-378|||Zykadia', u'Ceritinib (JAN/USAN/INN)', u'GTPL7397', u'SCHEMBL1014329', u'DTXSID10725373', u'EX-A187', u'SYN1199', u'VERWOWGGCGHDQE-UHFFFAOYSA-N', u'HMS3652H22', u'AOB31713', u'BCP07611', u'2510AH', u'BDBM50436850', u'MFCD26142648', u'ZINC96272772', u'AKOS025396438', u'CS-1406', u'DB09063', u'GS-6356', u'QC-5183', u'SB16490', u'compound 15b [PMID 23742252]', u'NCGC00351603-10', u'NCGC00351603-15', u'2,4-Pyrimidinediamine, 5-chloro-N4-(2-((1-methylethyl)sulfonyl)phenyl)-N2-(5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl)-', u'4CA-0729', u'AC-27469', u'BC600329', u'HY-15656', u'SC-93949', u'AB0096053', u'FT-0697208', u'S7083', u'SW219725-1', u'D10551', u'W-6123', u'J-690011', u'N-{2-Methyl-5-[(methylamino)methyl]phenyl}-4-[(4-phenyl-2-quinazolinyl)amino]benzamide', u'4MK', u'5-chloro-N(2)-{5-methyl-4-(piperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N(4)-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine', u'5-Chloro-N~2~-{5-methyl-4-(piperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine', u'5-Chloro-N2-(2-isopropoxy-5-methyl-4-piperidin-4-yl-phenyl)-N4-[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine', u'N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamide', u'D04LVK', u'D0KJ9P', u'ACN-036295', u'4-(chloromethyl)-2-methyl-1,3-thiazole', u'A8328', u'A13238', u'C586847'], 2,4-Pyrimidinediamine, 5-chloro-N⁴-[2-[(1-methylethyl)sulfonyl]phenyl]-N²-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-, 5-Chloro-N4-(2-((1-Methylethyl)Sulfonyl)Phenyl)-N2-(5-Methyl-2-(1-Methylethoxy)-4-(4-Piperidinyl)Phenyl)-2,4-Pyrimidinediamine, 5-Chloro-N⁴-[2-[(1-methylethyl)sulfonyl]phenyl]-N²-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine, Ldk 378, Ldk378, Zykadia
• CAS: 1032900-25-6
• Brand: Indagoo

Chemical properties

• Molecular weight: 558.1351
• Formula: C₂₈H₃₆ClN₅O₃S
• Purity: 98%
• Color/Form: Solid
• InChI: InChI=1S/C28H36ClN5O3S/c1-17(2)37-25-15-21(20-10-12-30-13-11-20)19(5)14-24(25)33-28-31-16-22(29)27(34-28)32-23-8-6-7-9-26(23)38(35,36)18(3)4/h6-9,14-18,20,30H,10-13H2,1-5H3,(H2,31,32,33,34)
• InChI key: VERWOWGGCGHDQE-UHFFFAOYSA-N