Betulinic acid

CAS: 472-15-1

Ref. BP-BP0271

Product Information

• Name: Betulinic acid
• Synonyms: Melaleucin, Mairin, Gratiolone, Platanol, Platanolic acid, Betulic acid, (1R,3aS,5bS,9R,11aR,13aS)-9-hydroxy-5b,8,8,11a-tetramethyl-1-(1-methylethenyl)icosahydro-3aH-cyclopenta[a]chrysene-3a-carboxylic acid, (3Beta)-3-Hydroxylup-20(29)-En-28-Oic Acid, (3Beta,5Xi,9Xi,13Xi,18Xi)-3-Hydroxylup-20(29)-En-28-Oic Acid, (3β)-3-Hydroxylup-20(29)-en-28-oic acid, 3-Hydroxylup-20(29)-en-28-oic acid, 3aH-Cyclopenta[a]chrysene, lup-20(29)-en-28-oic acid deriv., 3β-Hydroxylup-20(29)-en-28-oic acid, Acide Lupene-20(29) Oique-28, Hydroxy-3, (3Β)-, Acido Lup-20(29)-En-28-Oico, 3-Hidroxi-, (3Β)-, Ccris 6748, Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3beta)-, Lup-20(29)-en-28-oic acid, 3-hydroxy-, (3β)-, Lup-20(29)-en-28-oic acid, 3beta-hydroxy-, Lup-20(29)-en-28-oic acid, 3β-hydroxy-, Lup-20(29)-en-28-olsaure, 3-Hydroxy-, (3β)-, Lupatic acid, Nsc 113090, Nsc 677578, β-Betulinic acid

Description

Betulinic acid is a natural pentacyclic triterpenoid, acts as a eukaryotic topoisomerase I inhibitor, with an IC50 of 5 μM, and possesses anti-HIV, anti-malarial, immunomodulatory, anti-inflammatory and anti-tumor properties.Betulinic acid is a selective inducer of apoptosis in tumor cells, it inhibits activation of NF-kappaB and NF-kappaB-regulated gene expression induced by carcinogens and inflammatory stimuli.

• Brand: Biopurify

Chemical properties

• Molecular weight: 456.711
• Formula: C₃₀H₄₈O₃
• Purity: 95%~99%