Echinatin

CAS: 34221-41-5

Ref. BP-BP0521

Product Information

• Name: Echinatin
• Synonyms: 4'-Dihydroxy-2-methoxychalcone, (E)-4,4'-Dihydroxy-2-methoxychalcone, 2-propen-1-one, 3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-, 34221-41-5, 4,4'-Dihydroxy-2-Methoxychalcone

Description

Echinatin has significant antioxidant and anti-inflammary activities, it shows strong scavenging activity toward the ABTS + radical, it also inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells. Echinatin disturbs the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity.

• Brand: Biopurify

Chemical properties

• Molecular weight: 270.284
• Formula: C₁₆H₁₄O₄
• Purity: 95%~99%
• InChI: InChI=1S/C16H14O4/c1-20-16-10-14(18)8-4-12(16)5-9-15(19)11-2-6-13(17)7-3-11/h2-10,17-18H,1H3/b9-5+
• InChI key: InChIKey=QJKMIJNRNRLQSS-WEVVVXLNSA-N
• SMILES: COc1cc(O)ccc1/C=C/C(=O)c1ccc(O)cc1