Sakuranetin

CAS: 2957-21-3

Ref. BP-BP1243

Product Information

• Name: Sakuranetin
• Synonyms: (-)-(S)-Sakuranetin, (2S)-2,3-Dihydro-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one, (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one, (S)-4′,5-Dihydroxy-7-methoxyflavanone, 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, (2S)-, 4H-1-Benzopyran-4-one, 2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-, (S)-, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one, 7-O-Methylnaringenin, Flavanone, 4′,5-dihydroxy-7-methoxy-, (S)-(-)-, Naringenin 7-O-methyl ether, Naringenin 7-methyl ether

Description

Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant effects, it shows a suppressive effect on umu gene expression of SOS response in Salmonella typhimurium TA1535/pSK1002 against the mutagen furylfuramide. Sakuranetin may contribute to maintain glucose homeostasis in animals, it can strongly induce differentiation of 3T3-L1 preadipocytes, stimulate glucose uptake in differentiated 3T3-L1 adipocytes.Sakuranetin stimulates melanogenesis in B16 melanoma cells via inhibition of ERK1/2 and PI3K/AKT signaling pathways, which lead to upregulation of Tyr, TRP1, and TRP2.

• Brand: Biopurify

Chemical properties

• Molecular weight: 286.283
• Formula: C₁₆H₁₄O₅
• Purity: 95%~99%
• InChI: InChI=1S/C16H14O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-7,14,17-18H,8H2,1H3/t14-/m0/s1
• InChI key: InChIKey=DJOJDHGQRNZXQQ-AWEZNQCLSA-N
• SMILES: COc1cc(O)c2c(c1)O[C@H](c1ccc(O)cc1)CC2=O