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Euscaphic acid and tormentic acid from the roots of Rosa rugosa have inhibitory effect on high fat diet-induced obesity in the rat.
Euscaphic acid has anti-contraction effects on rat's aortic smooth muscle.
Euscaphic acid, isolated from roots of Rosa rugosa, inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.
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Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
 Mahmud S A. Adv Life Sci Technol, 2015, 33.
analysis-method: HPLC-DAD or/and HPLC-ELSD
botanical-source: Euscaphis japonica
identification-method: Mass, NMR
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