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Flavokawain B

CAS:

Ref. BP-BP3146

20mg
81.00€
100mg
235.00€
Flavokawain B
Biopurify

Product Information

Name:Flavokawain B
Brand:Biopurify
Description:Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. Flavokawain B has potent anti-inflammatory, and anti-cancer activities, it can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:284.311
Formula:C17H16O4
Purity:95%~99%
Color/Form:Yellow powder
InChI:InChI=1S/C17H16O4/c1-20-13-10-15(19)17(16(11-13)21-2)14(18)9-8-12-6-4-3-5-7-12/h3-11,19H,1-2H3/b9-8+
InChI key:InChIKey=QKQLSQLKXBHUSO-CMDGGOBGSA-N
SMILES:COc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OC)c1

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