Loureirin A

CAS: 119425-89-7

Ref. BP-BP3235

Product Information

• Name: Loureirin A
• Synonyms: 1-Propanone, 3-(2,4-Dimethoxyphenyl)-1-(4-Hydroxyphenyl)-, 3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone, 4′-Hydroxy-2,4-dimethoxydihydrochalcone, 3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one

Description

Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs.

• Brand: Biopurify

Chemical properties

• Molecular weight: 286.327
• Formula: C₁₇H₁₈O₄
• Purity: 95%~99%
• Color/Form: Powder
• InChI: InChI=1S/C17H18O4/c1-20-15-9-5-13(17(11-15)21-2)6-10-16(19)12-3-7-14(18)8-4-12/h3-5,7-9,11,18H,6,10H2,1-2H3
• InChI key: InChIKey=RSAIVLRELNGZEY-UHFFFAOYSA-N
• SMILES: COc1ccc(CCC(=O)c2ccc(O)cc2)c(OC)c1