Kininogen 1 Rabbit pAb
Ref. EK-EA367
Product Information
Name:Kininogen 1 Rabbit pAb
Synonyms:
- BDK
- Fitzgerald factor
- HMWK
- Ile Ser Bradykinin Bradykinin
- Kallidin I Lysyl bradykinin
- kininogen 1
- KNG
- KNG1
Brand:ELK Biotechnology
Description:Kininogens are inhibitors of thiol proteases; HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids. UCHL1 is abundantly expressed in neuronal tissues and testes.
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Chemical properties
Technical inquiry about: Kininogen 1 Rabbit pAb
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