HSP70 Mouse mAb
Ref. EK-EM1042
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- Heat shock 70 kDa protein 1/2
- heat shock 70kDa protein 1A
- HSP70
- HSP70 1
- HSP70 1/HSP70 2
- HSP70 1A
- HSP70.1/HSP70.2
- HSP70I
- HSP72
- HSPA1
- See more synonyms
- HSPA1A
- HSPA1B
The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity, such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes, the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues, and interacts with them. This spontaneous interaction is reversible, and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However, the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70, increasing its normally slow rate of ATP hydrolysis.
Chemical properties
Technical inquiry about: EK-EM1042 HSP70 Mouse mAb
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
