CK16 Mouse mAb
Ref. EK-EM1056
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- Cytokeratin 16
- K16
- K1CP
- keratin 16
- KRT16
- KRT16A
- NEPPK
Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Chemical properties
Technical inquiry about: EK-EM1056 CK16 Mouse mAb
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