PARP Mouse mAb
Ref. EK-EM1131
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- PARP-1
- Poly(ADP ribose) polymerase 1
- sPARP1,ADPRT1
- ADP ribosyltransferase NAD(+)
Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
Chemical properties
Technical inquiry about: EK-EM1131 PARP Mouse mAb
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