Cleaved PARP Mouse mAb
Ref. EK-EM1132
Product Information
Name:Cleaved PARP Mouse mAb
Synonyms:
- PARP-1
- Poly(ADP ribose) polymerase 1
- sPARP1,ADPRT1
- ADP ribosyltransferase NAD(+)
Brand:ELK Biotechnology
Description:Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Technical inquiry about: Cleaved PARP Mouse mAb
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