Cleaved-Plasma Kallikrein HC (R390) rabbit pAb
Ref. EK-ES1072
Product Information
Name:Cleaved-Plasma Kallikrein HC (R390) rabbit pAb
Synonyms:
- KLKB1; KLK3; Plasma kallikrein; Fletcher factor; Kininogenin; Plasma prekallikrein
Brand:ELK Biotechnology
Description:This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
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Chemical properties
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