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GPX3 rabbit pAb

Ref. EK-ES10932

50µl
188.00 €
100µl
316.00 €
Estimated delivery in United States, on Friday 19 Jul 2024

Product Information

Name:
GPX3 rabbit pAb
Description:

The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is secreted, and is abundantly found in plasma. Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies, including thyroid cancer, hepatocellular carcinoma and chronic myeloid leukemia. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designa

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Our products are intended for lab use only. For any other use, please contact us.
Brand:
ELK Biotechnology
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Hazard Info

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