ANTR1 rabbit pAb
Ref. EK-ES11151
50µl
188.00€
100µl
316.00€
Product Information
Name:ANTR1 rabbit pAb
Brand:ELK Biotechnology
Description:This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008],
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Chemical properties
Technical inquiry about: ANTR1 rabbit pAb
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