LN28B rabbit pAb
Ref. EK-ES11243
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012],
Chemical properties
Technical inquiry about: EK-ES11243 LN28B rabbit pAb
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