SMAD7 rabbit pAb
Ref. EK-ES11276
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
Chemical properties
Technical inquiry about: EK-ES11276 SMAD7 rabbit pAb
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