ZBT7A rabbit pAb
Ref. EK-ES11928
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
function:Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with BCL6.,tissue specificity:Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).,
Chemical properties
Technical inquiry about: EK-ES11928 ZBT7A rabbit pAb
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