HDAC5 (phospho Ser498) rabbit pAb
Ref. EK-ES1324
Product Information
Name:HDAC5 (phospho Ser498) rabbit pAb
Synonyms:
- HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
Brand:ELK Biotechnology
Description:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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