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REN3A rabbit pAb

Ref. EK-ES13427

50µl
188.00 €
100µl
316.00 €
Estimated delivery in United States, on Tuesday 3 Dec 2024

Product Information

Name:
REN3A rabbit pAb
Description:

This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

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Our products are intended for lab use only. For any other use, please contact us.
Brand:
ELK Biotechnology
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