Stat4 (phospho Tyr693) rabbit pAb
Ref. EK-ES1407
Product Information
Name:Stat4 (phospho Tyr693) rabbit pAb
Synonyms:
- STAT4; Signal transducer and activator of transcription 4
Brand:ELK Biotechnology
Description:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
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Chemical properties
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