Stat6 (phospho Tyr641) rabbit pAb
Ref. EK-ES1409
50µl
188.00€
100µl
316.00€
Product Information
Name:Stat6 (phospho Tyr641) rabbit pAb
Synonyms:
- STAT6; Signal transducer and activator of transcription 6; IL-4 Stat
Brand:ELK Biotechnology
Description:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
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