EpoR (phospho Tyr426) rabbit pAb
Ref. EK-ES1538
50µl
188.00€
100µl
316.00€
Product Information
Name:EpoR (phospho Tyr426) rabbit pAb
Synonyms:
- EPOR; Erythropoietin receptor; EPO-R
Brand:ELK Biotechnology
Description:This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010],
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