

CFAD (Cleaved-Ile26) rabbit pAb
Ref. EK-ES19983
50µl
188.00€
100µl
316.00€


Product Information
Name:CFAD (Cleaved-Ile26) rabbit pAb
Synonyms:
- Complement factor D (EC 3.4.21.46;Adipsin;C3 convertase activator;Properdin factor D)
Brand:ELK Biotechnology
Description:catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Technical inquiry about: CFAD (Cleaved-Ile26) rabbit pAb
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