ITGA2B (heavy chain, Cleaved-Leu32) rabbit pAb
Ref. EK-ES20011
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- Integrin alpha-IIb (GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain
- form 1; Integrin alpha-IIb light chain
- form 2]
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
Chemical properties
Technical inquiry about: EK-ES20011 ITGA2B (heavy chain, Cleaved-Leu32) rabbit pAb
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