ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb
Ref. EK-ES20012
Product Information
Name:ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb
Synonyms:
- Integrin alpha-IIb (GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain
- form 1; Integrin alpha-IIb light chain
- form 2]
Brand:ELK Biotechnology
Description:This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],
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Chemical properties
Technical inquiry about: ITGA2B (light chain form 1, Cleaved-Gln891) rabbit pAb
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