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CLK2 rabbit pAb

Ref. EK-ES2002

50µl
188.00€
100µl
316.00€
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ELK Biotechnology

Product Information

Name:CLK2 rabbit pAb
Synonyms:
  • CLK2; Dual specificity protein kinase CLK2; CDC-like kinase 2
Brand:ELK Biotechnology
Description:CDC like kinase 2(CLK2) Homo sapiens This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
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