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MMP8 (Cleaved-Leu101) rabbit pAb

Ref. EK-ES20030

50µl
188.00€
100µl
316.00€
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ELK Biotechnology

Product Information

Name:MMP8 (Cleaved-Leu101) rabbit pAb
Synonyms:
  • Neutrophil collagenase (EC 3.4.24.34;Matrix metalloproteinase-8;MMP-8;PMNL collagenase;PMNL-CL)
Brand:ELK Biotechnology
Description:catalytic activity:Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 3 calcium ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,enzyme regulation:Cannot be activated without removal of the activation peptide.,function:Can degrade fibrillar type I, II, and III collagens.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,subcellular location:Stored in intracellular granules.,tissue specificity:Neutrophils.,
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Technical inquiry about: MMP8 (Cleaved-Leu101) rabbit pAb

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