p21 (Acetyl Lys161/K163) rabbit pAb
Ref. EK-ES20121
50µl
188.00€
100µl
316.00€
Product Information
Name:p21 (Acetyl Lys161/K163) rabbit pAb
Synonyms:
- Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1;Melanoma differentiation-associated protein 6;MDA-6;p21)
Brand:ELK Biotechnology
Description:function:May be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.,induction:By p53, mezerein (antileukemic compound) and interferon beta.,PTM:Phosphorylation of Thr-145 by Akt or of Ser-146 by PKC impairs binding to PCNA.,similarity:Belongs to the CDI family.,tissue specificity:Expressed in all adult human tissues, with 5-fold lower levels observed in the brain.,
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
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