DNA pol β (Acetyl Lys72) rabbit pAb
Ref. EK-ES20123
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- DNA polymerase beta (EC 2.7.7.7;EC 4.2.99.-)
catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,
Chemical properties
Technical inquiry about: EK-ES20123 DNA pol β (Acetyl Lys72) rabbit pAb
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