Pdcd-1 rabbit pAb
Ref. EK-ES20278
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- Programmed cell death protein 1 (Protein PD-1;hPD-1;CD antigen CD279)
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],
Chemical properties
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