Bmi-1 Rabbit rabbit pAb(F270)
Ref. EK-ES20814
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
BMI1 proto-oncogene, polycomb ring finger(BMI1) Homo sapiens This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene. [provided by RefSeq, Sep 2015],
Chemical properties
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