E2F-2 rabbit pAb
Ref. EK-ES2212
50µl
188.00€
100µl
316.00€
Product Information
Name:E2F-2 rabbit pAb
Synonyms:
- E2F2; Transcription factor E2F2; E2F-2
Brand:ELK Biotechnology
Description:The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits
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Chemical properties
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