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Integrin αV rabbit pAb

Ref. EK-ES2629

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ELK Biotechnology

Product Information

Name:Integrin αV rabbit pAb
Synonyms:
  • ITGAV; MSK8; VNRA; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51
Brand:ELK Biotechnology
Description:integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],
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