JMY rabbit pAb
Ref. EK-ES2661
Product Information
Name:JMY rabbit pAb
Synonyms:
- JMY; Junction-mediating and -regulatory protein
Brand:ELK Biotechnology
Description:function:Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage.,induction:By E2F.,PTM:Ubiquitinated by MDM2, leading to its subsequent degradation by the proteasome. In case of DNA damage, the interaction with MDM2 is altered, preventing degradation and allowing interaction with p300/EP300 and its function in p53/TP53 stress response.,similarity:Contains 1 WH2 domain.,subunit:Interacts with p300/EP300, the complex being recruited to activated p53/TP53. Interacts with TTC5.,
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Chemical properties
Technical inquiry about: JMY rabbit pAb
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