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mGluR-7 rabbit pAb

Ref. EK-ES2787

50µl
188.00 €
100µl
316.00 €
Estimated delivery in United States, on Monday 16 Dec 2024

Product Information

Name:
mGluR-7 rabbit pAb
Synonyms:
  • GRM7; GPRC1G; MGLUR7; Metabotropic glutamate receptor 7; mGluR7
Description:

glutamate metabotropic receptor 7(GRM7) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
ELK Biotechnology
Long term storage:
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