ST5 rabbit pAb
Ref. EK-ES3505
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- ST5; DENND2B; HTS1; Suppression of tumorigenicity 5 protein; DENN domain-containing protein 2B; HeLa tumor suppression 1
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008],
Chemical properties
Technical inquiry about: EK-ES3505 ST5 rabbit pAb
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