NPRL2 rabbit pAb
Ref. EK-ES3816
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- NPRL2; TUSC4; Nitrogen permease regulator 2-like protein; NPR2-like protein; Gene 21 protein; G21 protein; Tumor suppressor candidate 4
function:Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.,similarity:Belongs to the NPR2 family.,subunit:Interacts with PDPK1.,tissue specificity:Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested.,
Chemical properties
Technical inquiry about: EK-ES3816 NPRL2 rabbit pAb
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