CD207 rabbit pAb
Ref. EK-ES4005
50µl
188.00€
100µl
316.00€
Product Information
Name:CD207 rabbit pAb
Synonyms:
- CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
Brand:ELK Biotechnology
Description:The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],
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