SDHB rabbit pAb
Ref. EK-ES4180
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- SDHB; SDH; SDH1; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit
- mitochondrial; Iron-sulfur subunit of complex II; Ip
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008],
Chemical properties
Technical inquiry about: EK-ES4180 SDHB rabbit pAb
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