GDF-6 rabbit pAb
Ref. EK-ES4378
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- GDF6; GDF16; Growth/differentiation factor 6; GDF-6; Growth/differentiation factor 16
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],
Chemical properties
Technical inquiry about: EK-ES4378 GDF-6 rabbit pAb
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