

Sgo2 rabbit pAb
Ref. EK-ES4904


Product Information
Name:Sgo2 rabbit pAb
Synonyms:
- SGOL2; Shugoshin-like 2; Shugoshin-2; Sgo2; Tripin
Brand:ELK Biotechnology
Description:function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,
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Chemical properties
Technical inquiry about: Sgo2 rabbit pAb
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