Sgo2 rabbit pAb
Ref. EK-ES4904
50µl | 188.00 € | ||
100µl | 316.00 € |
Product Information
- SGOL2; Shugoshin-like 2; Shugoshin-2; Sgo2; Tripin
function:During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the shugoshin family.,subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase.,subunit:Directly interacts with PPP2CA.,
Chemical properties
Technical inquiry about: EK-ES4904 Sgo2 rabbit pAb
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