APOBEC3A rabbit pAb
Ref. EK-ES5099
Product Information
Name:APOBEC3A rabbit pAb
Synonyms:
- APOBEC3A; Probable DNA dC->dU-editing enzyme APOBEC-3A; Phorbolin-1
Brand:ELK Biotechnology
Description:This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b
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