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FGFR-3 rabbit pAb

Ref. EK-ES5249

50µl
188.00€
100µl
316.00€
CymitQuimica logo
ELK Biotechnology

Product Information

Name:FGFR-3 rabbit pAb
Synonyms:
  • FGFR3; JTK4; Fibroblast growth factor receptor 3; FGFR-3; CD antigen CD333
Brand:ELK Biotechnology
Description:This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys
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Chemical properties

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