KLHL3 rabbit pAb
Ref. EK-ES5478
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- KLHL3; KIAA1129; Kelch-like protein 3
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012],
Chemical properties
Technical inquiry about: EK-ES5478 KLHL3 rabbit pAb
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