APC (phospho Ser2054) rabbit pAb
Ref. EK-ES5768
50µl
188.00€
100µl
316.00€
Product Information
Name:APC (phospho Ser2054) rabbit pAb
Synonyms:
- APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5
Brand:ELK Biotechnology
Description:This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Jul 2008],
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