Arrestin-β-1 rabbit pAb
Ref. EK-ES6148
| 50µl | 188.00 € | ||
| 100µl | 316.00 € |
Product Information
- ARRB1; ARR1; Beta-arrestin-1; Arrestin beta-1
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011],
Chemical properties
Technical inquiry about: EK-ES6148 Arrestin-β-1 rabbit pAb
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